Estimating the Effective Number of Breeders From Heterozygote Excess in Progeny
نویسندگان
چکیده
منابع مشابه
On the potential for estimating the effective number of breeders from heterozygote-excess in progeny.
The important parameter of effective population size is rarely estimable directly from demographic data. Indirect estimates of effective population size may be made from genetic data such as temporal variation of allelic frequencies or linkage disequilibrium in cohorts. We suggest here that an indirect estimate of the effective number of breeders might be based on the excess of heterozygosity e...
متن کاملEstimating the effective number of breeders from heterozygote excess in progeny.
The heterozygote-excess method is a recently published method for estimating the effective population size (Ne). It is based on the following principle: When the effective number of breeders (Neb) in a population is small, the allele frequencies will (by chance) be different in males and females, which causes an excess of heterozygotes in the progeny with respect to Hardy-Weinberg equilibrium e...
متن کاملNb_HetEx: a program to estimate the effective number of breeders.
The program "Nb_HetEx" estimates the effective number of breeders (N(b)) that produced the sampled progeny based on genotype counts contained in that sample. When the number of breeders is very small, there is an excess of heterozygotes in their progeny: the smaller the number of breeders, the larger the heterozygote excess. The Nb_HetEx program also estimates N(e) through the temporal method.
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iii ACKNOWLEDGEMENTS I want to thank my advisor, Andrew Whiteley, for all of his encouragement and support throughout my graduate studies: for taking me on as a student, supporting me as a research assistant, helping me understand the concepts described in this thesis and patiently guiding me through this research. I also want to express my sincere thanks to my committee members Ben Letcher and...
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ژورنال
عنوان ژورنال: Genetics
سال: 1999
ISSN: 1943-2631
DOI: 10.1093/genetics/151.3.1211